Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu logo faccejpi Déroulé - logo Faccejpi


Zone de texte éditable et éditée et rééditée

Understanding the development and control of stability in the rumen microbiome as a basis for new strategies to reduce methanogenesis

Richard Dewhurst (coordinator)


The project will identify and exploit long-term effects of short-duration dietary treatments on methane production, rumen function and responses to methane mitigation interventions at a later stage. There will be a focus on manipulations in early life, when the rumen community is developing, but also work on other diet transitions. The idea is to reduce the cost and effort of mitigation strategies by reducing the duration and/or quantity of treatment required and/or to increase the size of responses if treatments have to be reapplied. Whilst earlier studies with young ruminants have used potent anti-methanogenic compounds, this work focuses on the residual effects of some of the dramatic diet transitions experienced on-farm, including weaning and transitions to grazing or high-density finishing diets. This project addresses effects of management history on the interaction between the host and its microbiome and on methane production. The ability to identify differences between animals makes the work highly complementary to existing programs on the effects of host genetics/genomics on methane production. We will build on recent work showing residual anti-methanogenic effects of bromochloromethane administered to goat kids. Our primary hypothesis is that the initial microbial implantation in the rumen influences the microbial ecosystem later in life. One aspect of this is transfer of the maternal microbiome to offspring, which may contribute to stability of the rumen microbiome in later life (e.g. reversion to the original community after rumen swapping). We will extend the work on stability of the rumen microbiome to important diet transitions in growing/adult animals. We will use state-of-the-art immunology to test our second hypothesis, that differences in the rumen microbiome in early life affect the development of the host immune response to the microbiome. We will use a combination of the most current and cost-effective techniques to profile the short- and long-term responses of the rumen microbiome diversity and activity, focusing analysis where treatments have shown a clear effect on methane production. We will also address the need for biomarkers for the establishment of methanogenesis using both targeted (archaeol) and non-targeted metabolomics with faeces, rumen fluid, urine and blood. There are five components to the work:
1. New animal studies – investigating long-term effects of previous dietary treatments or anti-methanogenic additives on methane production. These will include studies around weaning, as well as in adult life - with commercially relevant treatments;
2. Additional analysis of samples from new/existing studies to help interpret responses. These may be run by the partner conducting the study or facilitated through exchange of samples.
3. Workshops and short-term visits for training in new methods and standardisation of methodology.
4. Evaluation of the economic viability of strategies identified in the project.
5. Dissemination of results and recommendations to stake-holders and policy makers.